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DGM1

Services

Dynamic Gastric Model Services by Our Partner – Bioneer

For organisations that prefer not to conduct studies in-house, or where independent execution is required, studies utilising the Dynamic Gastric Model (DGM) can be conducted separately by Bioneer a centre of excellence for gastro-intestinal (GI) modelling.


While DGM units are supplied to the research community for internal use, it is common for industry-based projects to require studies to be performed by an external, independent organisation with established experience operating the Dynamic Gastric Model. In such cases, Bioneer designs and conducts DGM studies, applying defined experimental protocols and interpreting results based on their practical experience with the model. Typical customers include pharmaceutical and biotech companies looking to optimise oral drug formulations, evaluate bioequivalence, study food effects, or reduce reliance on animal testing.


This dual approach allows organisations to balance long-term in-house capability with access to independent DGM studies, depending on the needs of each project.


Further details on Dynamic Gastric Model services are available at Bioneer.


Examples of Dynamic Gastric Model Use

Examples of how the DGM has been applied in pharmaceutical research and development are available through publicly accessible posters prepared by Bioneer. These materials describe specific case studies and experimental approaches using the DGM.


Selected examples include: 


Cataflam: Application of the Dynamic Gastric Model to investigate gastric behaviour under different feeding conditions


Mucinex 12-hour: Evaluation of formulation behaviour during simulated gastric digestion


These posters provide insight into study design, methodology, and outcomes, and illustrate how the Dynamic Gastric Model is applied in industry practice.


Industry use cases are also available to view here. 


Relationship Between DGM Equipment for Sale and Services

 We, Plant Bioscience Limited (PBL) supply Dynamic Gastric Model (DGM) units as research equipment.


Bioneer, under licence by PBL, independently delivers services, using the Dynamic Gastric Model (DGM).


This supports:

  • Transparency between equipment provision and study execution
  • Flexibility in choosing in-house or externally conducted studies
  • Access to established experience in operating and interpreting Dynamic Gastric Model experiments


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